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Dexamethasone during pregnancy impairs maternal pancreatic β-cell renewal during lactation

Pancreatic islets from pregnant rats develop a transitory increase in the pancreatic β-cell proliferation rate and mass. Increased apoptosis during early lactation contributes to the rapid reversal of those morphological changes. Exposure to synthetic glucocorticoids during pregnancy has been previo...

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Detalles Bibliográficos
Autores principales: Teixeira, Caio Jordão, Santos-Silva, Junia Carolina, de Souza, Dailson Nogueira, Rafacho, Alex, Anhe, Gabriel Forato, Bordin, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376996/
https://www.ncbi.nlm.nih.gov/pubmed/30768422
http://dx.doi.org/10.1530/EC-18-0505