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Dexamethasone during pregnancy impairs maternal pancreatic β-cell renewal during lactation
Pancreatic islets from pregnant rats develop a transitory increase in the pancreatic β-cell proliferation rate and mass. Increased apoptosis during early lactation contributes to the rapid reversal of those morphological changes. Exposure to synthetic glucocorticoids during pregnancy has been previo...
Autores principales: | Teixeira, Caio Jordão, Santos-Silva, Junia Carolina, de Souza, Dailson Nogueira, Rafacho, Alex, Anhe, Gabriel Forato, Bordin, Silvana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376996/ https://www.ncbi.nlm.nih.gov/pubmed/30768422 http://dx.doi.org/10.1530/EC-18-0505 |
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