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An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking

In the U.S., more than 80% of African-American smokers use mentholated cigarettes, compared to less than 30% of Caucasian smokers. The reasons for these differences are not well understood. To determine if genetic variation contributes to mentholated cigarette smoking, we performed an exome-wide ass...

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Detalles Bibliográficos
Autores principales: Kozlitina, Julia, Risso, Davide, Lansu, Katherine, Olsen, Reid Hans Johnson, Sainz, Eduardo, Luiselli, Donata, Barik, Arnab, Frigerio-Domingues, Carlos, Pagani, Luca, Wooding, Stephen, Kirchner, Thomas, Niaura, Ray, Roth, Bryan, Drayna, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377114/
https://www.ncbi.nlm.nih.gov/pubmed/30768591
http://dx.doi.org/10.1371/journal.pgen.1007916