Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer

Ornithine decarboxylase (ODC) is the rate-limiting enzyme of polyamine synthesis. The two ODC antizyme inhibitors (AZIN1) and (AZIN2) are regulators of the catalytic activity of ODC. While AZIN1 is a regulator of cell proliferation, AZIN2 is involved in intracellular vesicle transport and secretion....

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Detalles Bibliográficos
Autores principales: Kaprio, Tuomas, Rasila, Tiina, Hagström, Jaana, Mustonen, Harri, Lankila, Petri, Haglund, Caj, Andersson, Leif C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377119/
https://www.ncbi.nlm.nih.gov/pubmed/30768610
http://dx.doi.org/10.1371/journal.pone.0211564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377119/
https://www.ncbi.nlm.nih.gov/pubmed/30768610
http://dx.doi.org/10.1371/journal.pone.0211564

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