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Huntingtin associates with the actin cytoskeleton and α-actinin isoforms to influence stimulus dependent morphology changes

One response of cells to growth factor stimulus involves changes in morphology driven by the actin cytoskeleton and actin associated proteins which regulate functions such as cell adhesion, motility and in neurons, synaptic plasticity. Previous studies suggest that Huntingtin may be involved in regu...

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Detalles Bibliográficos
Autores principales: Tousley, Adelaide, Iuliano, Maria, Weisman, Elizabeth, Sapp, Ellen, Richardson, Heather, Vodicka, Petr, Alexander, Jonathan, Aronin, Neil, DiFiglia, Marian, Kegel-Gleason, Kimberly B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377189/
https://www.ncbi.nlm.nih.gov/pubmed/30768638
http://dx.doi.org/10.1371/journal.pone.0212337