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A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution
In eukaryotes, ribosome profiling provides insight into the mechanism of protein synthesis at the codon level. In bacteria, however, the method has been more problematic and no consensus has emerged for how to best prepare profiling samples. Here, we identify the sources of these problems and descri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377232/ https://www.ncbi.nlm.nih.gov/pubmed/30724162 http://dx.doi.org/10.7554/eLife.42591 |