The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully understood. In proliferating cells, B-Myb interacts with the MuvB core complex inclu...

Descripción completa

Detalles Bibliográficos
Autores principales: Iness, Audra N., Felthousen, Jessica, Ananthapadmanabhan, Varsha, Sesay, Fatmata, Saini, Siddharth, Guiley, Keelan Z., Rubin, Seth M., Dozmorov, Mikhail, Litovchick, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377300/
https://www.ncbi.nlm.nih.gov/pubmed/30206359
http://dx.doi.org/10.1038/s41388-018-0490-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377300/
https://www.ncbi.nlm.nih.gov/pubmed/30206359
http://dx.doi.org/10.1038/s41388-018-0490-y

Ejemplares similares