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The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully understood. In proliferating cells, B-Myb interacts with the MuvB core complex inclu...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377300/ https://www.ncbi.nlm.nih.gov/pubmed/30206359 http://dx.doi.org/10.1038/s41388-018-0490-y |