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Inositol Polyphosphate 4-phosphatase Type II Regulation of Androgen Receptor Activity

Activation and transcriptional reprogramming of AR in advanced prostate cancer frequently coincides with the loss of two tumor suppressors, INPP4B and PTEN, which are highly expressed in human and mouse prostate epithelium. While regulation of AR signaling by PTEN has been described by multiple grou...

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Detalles Bibliográficos
Autores principales: Zhang, Manqi, Suarez, Egla, Vasquez, Judy L., Nathanson, Lubov, Peterson, Leif E., Rajapakshe, Kimal, Basil, Paul, Weigel, Nancy L., Coarfa, Cristian, Agoulnik, Irina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377303/
https://www.ncbi.nlm.nih.gov/pubmed/30228349
http://dx.doi.org/10.1038/s41388-018-0498-3