15-deoxy-Δ(12, 14)-prostaglandin J(2) enhances anticancer activities independently of VHL status in renal cell carcinomas

Renal cell carcinoma (RCC) is relatively resistant to chemotherapy and radiotherapy. Clear cell RCC (ccRCC) accounts for the majority of RCC, which have mutations or epigenetic silencing of the von Hippel–Lindau (VHL) gene. VHL-positive Caki-2 cells are killed by an endogenous anticancer substance,...

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Detalles Bibliográficos
Autores principales: Koma, Hiromi, Yamamoto, Yasuhiro, Fujita, Tomonari, Yagami, Tatsurou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377412/
https://www.ncbi.nlm.nih.gov/pubmed/30815591
http://dx.doi.org/10.1016/j.bbrep.2019.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377412/
https://www.ncbi.nlm.nih.gov/pubmed/30815591
http://dx.doi.org/10.1016/j.bbrep.2019.01.001

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