Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

Since Inhibitor of Apoptosis (IAP) proteins have been implicated in cellular adaptation to endoplasmic reticulum (ER) stress, we investigated the regulation of ER stress-induced apoptosis by small-molecule second mitochondria-derived activator of caspase (Smac) mimetics that antagonize IAP proteins....

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Detalles Bibliográficos
Autores principales: Abhari, Behnaz Ahangarian, McCarthy, Nicole, Le Berre, Marie, Kilcoyne, Michelle, Joshi, Lokesh, Agostinis, Patrizia, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377606/
https://www.ncbi.nlm.nih.gov/pubmed/30770792
http://dx.doi.org/10.1038/s41419-019-1381-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377606/
https://www.ncbi.nlm.nih.gov/pubmed/30770792
http://dx.doi.org/10.1038/s41419-019-1381-z

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