Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection

Recent studies have documented the diverse role of host immunity in infection by the protozoan parasite, Toxoplasma gondii. However, the contribution of the β-catenin pathway in this process has not been explored. Here, we show that AKT-mediated phosphorylated β-catenin supports T. gondii multiplica...

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Detalles Bibliográficos
Autores principales: Majumdar, Tanmay, Sharma, Shagun, Kumar, Manmohan, Hussain, Md. Arafat, Chauhan, Namita, Kalia, Inderjeet, Sahu, Amit Kumar, Rana, Vipin Singh, Bharti, Ruchi, Haldar, Arun Kumar, Singh, Agam P., Mazumder, Shibnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377608/
https://www.ncbi.nlm.nih.gov/pubmed/30770800
http://dx.doi.org/10.1038/s41419-019-1420-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377608/
https://www.ncbi.nlm.nih.gov/pubmed/30770800
http://dx.doi.org/10.1038/s41419-019-1420-9

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