Phenazine production promotes antibiotic tolerance and metabolic heterogeneity in Pseudomonas aeruginosa biofilms

Antibiotic efficacy can be antagonized by bioactive metabolites and other drugs present at infection sites. Pseudomonas aeruginosa, a common cause of biofilm-based infections, releases metabolites called phenazines that accept electrons to support cellular redox balancing. Here, we find that phenazi...

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Detalles Bibliográficos
Autores principales: Schiessl, Konstanze T., Hu, Fanghao, Jo, Jeanyoung, Nazia, Sakila Z., Wang, Bryan, Price-Whelan, Alexa, Min, Wei, Dietrich, Lars E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377615/
https://www.ncbi.nlm.nih.gov/pubmed/30770834
http://dx.doi.org/10.1038/s41467-019-08733-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377615/
https://www.ncbi.nlm.nih.gov/pubmed/30770834
http://dx.doi.org/10.1038/s41467-019-08733-w

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