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Genomic landscape of a metastatic malignant proliferating tricholemmal tumor and its response to PI3K inhibition

Proliferating tricholemmal tumors (PTTs) are rare benign neoplasms that arise from the outer sheath of a hair follicle. Occasionally, these PTTs undergo malignant transformation to become malignant proliferating tricholemmal tumors (MPTTs). Little is known about the molecular alterations, malignant...

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Detalles Bibliográficos
Autores principales: Gallant, Jean-Nicolas, Sewell, Andrew, Almodovar, Karinna, Wang, Qingguo, Dahlman, Kimberly B., Abramson, Richard G., Kapp, Meghan E., Brown, Brandee T., Boyd, Kelli L., Gilbert, Jill, Cohen, Daniel N., Yarbrough, Wendell G., Zhao, Zhongming, Lovly, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377617/
https://www.ncbi.nlm.nih.gov/pubmed/30793038
http://dx.doi.org/10.1038/s41698-019-0077-2