Sphingomyelin synthase 2 promotes an aggressive breast cancer phenotype by disrupting the homoeostasis of ceramide and sphingomyelin

Breast cancer is the most common type of carcinoma in women worldwide, but the mechanisms underlying tumour development and progression remain unclear. Sphingomyelin synthase 2 (SGMS2) is a crucial regulator involved in ceramide (Cer) and sphingomyelin (SM) homoeostasis that is mostly studied for it...

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Detalles Bibliográficos
Autores principales: Zheng, Kehong, Chen, Zetao, Feng, Haizhan, Chen, Ying, Zhang, Cheng, Yu, Jinlong, Luo, Yunfeng, Zhao, Liang, Jiang, Xiancheng, Shi, Fujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377618/
https://www.ncbi.nlm.nih.gov/pubmed/30770781
http://dx.doi.org/10.1038/s41419-019-1303-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377618/
https://www.ncbi.nlm.nih.gov/pubmed/30770781
http://dx.doi.org/10.1038/s41419-019-1303-0

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