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Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer
Primary triple negative breast cancers (TNBC) are prone to dissemination but sub-clonal relationships between tumors and resulting metastases are poorly understood. Here we use cellular barcoding of two treatment-naïve TNBC patient-derived xenografts (PDXs) to track the spatio-temporal fate of thous...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377663/ https://www.ncbi.nlm.nih.gov/pubmed/30770823 http://dx.doi.org/10.1038/s41467-019-08595-2 |