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Establishing a generalized polyepigenetic biomarker for tobacco smoking

Large-scale epigenome-wide association meta-analyses have identified multiple ‘signatures’’ of smoking. Drawing on these findings, we describe the construction of a polyepigenetic DNA methylation score that indexes smoking behavior and that can be utilized for multiple purposes in population health...

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Detalles Bibliográficos
Autores principales: Sugden, Karen, Hannon, Eilis J., Arseneault, Louise, Belsky, Daniel W., Broadbent, Jonathan M., Corcoran, David L., Hancox, Robert J., Houts, Renate M., Moffitt, Terrie E., Poulton, Richie, Prinz, Joseph A., Thomson, W. Murray, Williams, Benjamin S., Wong, Chloe C. Y., Mill, Jonathan, Caspi, Avshalom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377665/
https://www.ncbi.nlm.nih.gov/pubmed/30770782
http://dx.doi.org/10.1038/s41398-019-0430-9