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Establishing a generalized polyepigenetic biomarker for tobacco smoking
Large-scale epigenome-wide association meta-analyses have identified multiple ‘signatures’’ of smoking. Drawing on these findings, we describe the construction of a polyepigenetic DNA methylation score that indexes smoking behavior and that can be utilized for multiple purposes in population health...
Autores principales: | Sugden, Karen, Hannon, Eilis J., Arseneault, Louise, Belsky, Daniel W., Broadbent, Jonathan M., Corcoran, David L., Hancox, Robert J., Houts, Renate M., Moffitt, Terrie E., Poulton, Richie, Prinz, Joseph A., Thomson, W. Murray, Williams, Benjamin S., Wong, Chloe C. Y., Mill, Jonathan, Caspi, Avshalom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377665/ https://www.ncbi.nlm.nih.gov/pubmed/30770782 http://dx.doi.org/10.1038/s41398-019-0430-9 |
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