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ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

Serine/threonine phosphatases such as PP1 lack substrate specificity and associate with a large array of targeting subunits to achieve the requisite selectivity. The tumour suppressor ASPP (apoptosis-stimulating protein of p53) proteins associate with PP1 catalytic subunits and are implicated in mul...

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Detalles Bibliográficos
Autores principales: Bertran, M. Teresa, Mouilleron, Stéphane, Zhou, Yanxiang, Bajaj, Rakhi, Uliana, Federico, Kumar, Ganesan Senthil, van Drogen, Audrey, Lee, Rebecca, Banerjee, Jennifer J., Hauri, Simon, O’Reilly, Nicola, Gstaiger, Matthias, Page, Rebecca, Peti, Wolfgang, Tapon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377682/
https://www.ncbi.nlm.nih.gov/pubmed/30770806
http://dx.doi.org/10.1038/s41467-019-08686-0