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Parameter estimation in models of biological oscillators: an automated regularised estimation approach

BACKGROUND: Dynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These problems can be extremely...

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Detalles Bibliográficos
Autores principales: Pitt, Jake Alan, Banga, Julio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377730/
https://www.ncbi.nlm.nih.gov/pubmed/30770736
http://dx.doi.org/10.1186/s12859-019-2630-y