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Parameter estimation in models of biological oscillators: an automated regularised estimation approach
BACKGROUND: Dynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These problems can be extremely...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377730/ https://www.ncbi.nlm.nih.gov/pubmed/30770736 http://dx.doi.org/10.1186/s12859-019-2630-y |