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Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV

Latently infected CD4 lymphocytes preclude cure of HIV infection, even with the most effective antiretroviral therapy. The replication competent latent HIV reservoir has been quantified with the terminal dilution quantitative viral outgrowth assay, which induces virus propagation in CD4(+) T cell cu...

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Detalles Bibliográficos
Autores principales: Richman, Douglas D., Huang, Karissa, Lada, Steven M., Sun, Xiaoying, Jain, Sonia, Massanella, Marta, Menke, Bryson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377736/
https://www.ncbi.nlm.nih.gov/pubmed/30770748
http://dx.doi.org/10.1186/s12977-019-0466-1