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PLAIDOH: a novel method for functional prediction of long non-coding RNAs identifies cancer-specific LncRNA activities

BACKGROUND: Long non-coding RNAs (lncRNAs) exhibit remarkable cell-type specificity and disease association. LncRNA’s functional versatility includes epigenetic modification, nuclear domain organization, transcriptional control, regulation of RNA splicing and translation, and modulation of protein a...

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Detalles Bibliográficos
Autores principales: Pyfrom, Sarah C., Luo, Hong, Payton, Jacqueline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377765/
https://www.ncbi.nlm.nih.gov/pubmed/30767760
http://dx.doi.org/10.1186/s12864-019-5497-4