Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Holliday junction (HJ) resolution by its resolving enzymes is essential for chromosome segregation and recombination-mediated DNA repair. HJs undergo two types of structural dynamics that determine the outcome of recombination: conformer exchange between two isoforms and branch migration. However, i...

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Detalles Bibliográficos
Autores principales: Zhou, Ruobo, Yang, Olivia, Déclais, Anne-Cécile, Jin, Hyeonseok, Gwon, Gwang Hyeon, Freeman, Alasdair D. J., Cho, Yunje, Lilley, David M. J., Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377835/
https://www.ncbi.nlm.nih.gov/pubmed/30664685
http://dx.doi.org/10.1038/s41589-018-0209-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377835/
https://www.ncbi.nlm.nih.gov/pubmed/30664685
http://dx.doi.org/10.1038/s41589-018-0209-y

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