Cargando…

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Holliday junction (HJ) resolution by its resolving enzymes is essential for chromosome segregation and recombination-mediated DNA repair. HJs undergo two types of structural dynamics that determine the outcome of recombination: conformer exchange between two isoforms and branch migration. However, i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Ruobo, Yang, Olivia, Déclais, Anne-Cécile, Jin, Hyeonseok, Gwon, Gwang Hyeon, Freeman, Alasdair D. J., Cho, Yunje, Lilley, David M. J., Ha, Taekjip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377835/ https://www.ncbi.nlm.nih.gov/pubmed/30664685 http://dx.doi.org/10.1038/s41589-018-0209-y

Ejemplares similares

Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
por: Kaczmarczyk, Artur P., et al.
Publicado: (2022)

A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1
por: Liu, Yijin, et al.
Publicado: (2018)

GEN1 from a Thermophilic Fungus Is Functionally Closely Similar to Non-Eukaryotic Junction-Resolving Enzymes
por: Freeman, Alasdair D.J., et al.
Publicado: (2014)

Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure
por: Suzuki, Yuki, et al.
Publicado: (2014)

Characterization of the Holliday Junction Resolving Enzyme Encoded by the Bacillus subtilis Bacteriophage SPP1
por: Zecchi, Lisa, et al.
Publicado: (2012)

Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding
por: Freeman, Alasdair D. J., et al.
Publicado: (2016)

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases
por: Castor, Dennis, et al.
Publicado: (2013)

ruvA Mutants That Resolve Holliday Junctions but Do Not Reverse Replication Forks
por: Baharoglu, Zeynep, et al.
Publicado: (2008)

Molecular mechanism of double Holliday junction dissolution
por: Swuec, Paolo, et al.
Publicado: (2014)

Holliday junction resolution: Regulation in space and time
por: Matos, Joao, et al.
Publicado: (2014)

DNA Holliday Junction: History, Regulation and Bioactivity
por: Song, Qinqin, et al.
Publicado: (2022)

Double Holliday Junctions are Intermediates of DNA Break Repair
por: Bzymek, Malgorzata, et al.
Publicado: (2010)

Improved methods for creating migratable Holliday junction substrates
por: Chen, Stefanie Hartman, et al.
Publicado: (2013)

Integration Host Factor Binds DNA Holliday Junctions
por: Lin, Shawn H., et al.
Publicado: (2022)

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA
por: Liu, Yijin, et al.
Publicado: (2015)

Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines
por: LeRoy, Gary, et al.
Publicado: (2005)

Spermidine biases the resolution of Holliday junctions by phage λ integrase
por: Boldt, Jeffrey L., et al.
Publicado: (2007)

Holliday Junction Thermodynamics and Structure: Coarse-Grained Simulations and Experiments
por: Wang, Wujie, et al.
Publicado: (2016)

Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6
por: Ahlqvist, Josefin, et al.
Publicado: (2022)

The role of Holliday junction resolvases in the repair of spontaneous and induced DNA damage
por: Agmon, Neta, et al.
Publicado: (2011)

Crystal structure of RuvC resolvase in complex with Holliday junction substrate
por: Górecka, Karolina M., et al.
Publicado: (2013)

Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores
por: Shrestha, Prakash, et al.
Publicado: (2016)

Stretching DNA origami: effect of nicks and Holliday junctions on the axial stiffness
por: Jung, Wei-Hung, et al.
Publicado: (2020)

The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly
por: Simmons, Chad R., et al.
Publicado: (2022)

Molecular dynamics simulations of cyanine dimers attached to DNA Holliday junctions
por: Biaggne, Austin, et al.
Publicado: (2022)

Exciton Chirality Inversion in Dye Dimers Templated by DNA Holliday Junction
por: Mass, Olga A., et al.
Publicado: (2022)

Organometallic Pillarplexes That Bind DNA 4-Way Holliday Junctions and Forks
por: Craig, James S., et al.
Publicado: (2023)

The RecU Holliday junction resolvase acts at early stages of homologous recombination
por: Cañas, Cristina, et al.
Publicado: (2008)

Spatial control of the GEN1 Holliday junction resolvase ensures genome stability
por: Chan, Ying Wai, et al.
Publicado: (2014)

PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration
por: Baker, Christopher L., et al.
Publicado: (2014)

The structural ensemble of a Holliday junction determined by X-ray scattering interference
por: Zettl, Thomas, et al.
Publicado: (2020)

Targeted Therapy of Colon Cancer by Aptamer-Guided Holliday Junctions Loaded with Doxorubicin
por: Yao, Fengjiao, et al.
Publicado: (2020)

Canonical and novel non-canonical activities of the Holliday junction resolvase Yen1
por: Carreira, Raquel, et al.
Publicado: (2021)

Mechanism of AAA+ ATPase-mediated RuvAB–Holliday junction branch migration
por: Wald, Jiri, et al.
Publicado: (2022)

Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase
por: Xia, Jun, et al.
Publicado: (2016)

RusA Holliday junction resolvase: DNA complex structure—insights into selectivity and specificity
por: Macmaster, Rachel, et al.
Publicado: (2006)

Bacillus subtilis RecU Holliday-junction resolvase modulates RecA activities
por: Carrasco, Begoña, et al.
Publicado: (2005)

Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
por: Valente, Valeria, et al.
Publicado: (2013)

Meiotic Recombination in Neurospora crassa Proceeds by Two Pathways with Extensive Holliday Junction Migration
por: Yeadon, Patricia Jane, et al.
Publicado: (2016)

Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level
por: Sobhy, Mohamed A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ag9q6houp8greptkdvv2k5f84a