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Computational Causal Modeling of the Dynamic Biomarker Cascade in Alzheimer's Disease

BACKGROUND: Alzheimer's disease (AD) is a major public health concern, and there is an urgent need to better understand its complex biology and develop effective therapies. AD progression can be tracked in patients through validated imaging and spinal fluid biomarkers of pathology and neuronal...

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Detalles Bibliográficos
Autores principales: Petrella, Jeffrey R., Hao, Wenrui, Rao, Adithi, Doraiswamy, P. Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378032/
https://www.ncbi.nlm.nih.gov/pubmed/30863455
http://dx.doi.org/10.1155/2019/6216530