Flavonol 7-O-Glucoside Herbacitrin Inhibits HIV-1 Replication through Simultaneous Integrase and Reverse Transcriptase Inhibition

Here we report the evaluation of the antiretroviral effect of two flavonoid 7-O-glucosides, herbacitrin (1) and gossypitrin (2), together with quercetin (3), a well-studied flavonol. Antiviral activity of the flavonoids was assessed by analyzing HIV-1 p24 core protein levels in the supernatants of H...

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Detalles Bibliográficos
Autores principales: Áy, Éva, Hunyadi, Attila, Mezei, Mária, Minárovits, János, Hohmann, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378053/
https://www.ncbi.nlm.nih.gov/pubmed/30853999
http://dx.doi.org/10.1155/2019/1064793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378053/
https://www.ncbi.nlm.nih.gov/pubmed/30853999
http://dx.doi.org/10.1155/2019/1064793

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