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Rosiglitazone, a Ligand to PPARγ, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation

Rosiglitazone (RGZ), a peroxisome proliferator-activated receptor gamma (PPARγ) ligand, has been reported to act as insulin sensitizer and exert cardiovascular actions. In this work, we hypothesized that RGZ exerts a PPARγ–dependent regulation of blood pressure through modulation of angiotensin-conv...

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Detalles Bibliográficos
Autores principales: Sánchez-Aguilar, María, Ibarra-Lara, Luz, Del Valle-Mondragón, Leonardo, Rubio-Ruiz, María Esther, Aguilar-Navarro, Alicia G., Zamorano-Carrillo, Absalom, Ramírez-Ortega, Margarita del Carmen, Pastelín-Hernández, Gustavo, Sánchez-Mendoza, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378057/
https://www.ncbi.nlm.nih.gov/pubmed/30863432
http://dx.doi.org/10.1155/2019/1371758