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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia

BACKGROUND: Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, haemoglobin S (HbS) is formed, which modifies red blood cell morphology. Intravascular haemolysis occurs, in which free Hb and free radicals degrade nitric oxide (NO) and release arginase, which reduces...

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Detalles Bibliográficos
Autores principales: Eleutério, Renata M. N., Nascimento, Francisco O., Araújo, Tamara G., Castro, Marilena F., Filho, Tarcísio P. Almeida, Filho, Pedro A. Maia, Eleutério, José, Elias, Darcielle B. D., Lemes, Romélia P. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378076/
https://www.ncbi.nlm.nih.gov/pubmed/30853991
http://dx.doi.org/10.1155/2019/4397150