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ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer

The uncommonness of gallbladder cancer in the developed world has contributed to the generally poor understanding of the disease. Our integrated analysis of whole exome sequencing, copy number alterations, immunohistochemical, and phospho‐proteome array profiling indicates ERBB2 alterations in 40% e...

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Detalles Bibliográficos
Autores principales: Iyer, Prajish, Shrikhande, Shailesh V., Ranjan, Malika, Joshi, Asim, Gardi, Nilesh, Prasad, Ratnam, Dharavath, Bhasker, Thorat, Rahul, Salunkhe, Sameer, Sahoo, Bikram, Chandrani, Pratik, Kore, Hitesh, Mohanty, Bhabani, Chaudhari, Vikram, Choughule, Anuradha, Kawle, Dhananjay, Chaudhari, Pradip, Ingle, Arvind, Banavali, Shripad, Gera, Poonam, Ramadwar, Mukta R., Prabhash, Kumar, Barreto, Savio George, Dutt, Shilpee, Dutt, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378102/
https://www.ncbi.nlm.nih.gov/pubmed/30304546
http://dx.doi.org/10.1002/ijc.31916