Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation

The dopamine (DA) D2 receptor (D2R) is an important target for the treatment of neuropsychiatric disorders such as schizophrenia and Parkinson’s disease. However, the development of improved therapeutic strategies has been hampered by our incomplete understanding of this receptor’s downstream signal...

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Detalles Bibliográficos
Autores principales: Donthamsetti, Prashant, Gallo, Eduardo F., Buck, David C., Stahl, Edward L., Zhu, Ying, Lane, J. Robert, Bohn, Laura M., Neve, Kim A., Kellendonk, Christoph, Javitch, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378141/
https://www.ncbi.nlm.nih.gov/pubmed/30120413
http://dx.doi.org/10.1038/s41380-018-0212-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378141/
https://www.ncbi.nlm.nih.gov/pubmed/30120413
http://dx.doi.org/10.1038/s41380-018-0212-4

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