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Targeting nucleolin to obstruct vasculature feeding with an intelligent DNA nanorobot

A prototype of DNA nanorobot with the ability to transport molecular payloads was designed to target cancer cells in tissue culture. Moreover, a further step was taken to succeed in the first in vivo application of the DNA nanorobot for cancer therapy. The robot was constructed using aptamer and DNA...

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Detalles Bibliográficos
Autores principales: Li, Hua, Liu, Jin, Gu, Hongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378176/
https://www.ncbi.nlm.nih.gov/pubmed/30592140
http://dx.doi.org/10.1111/jcmm.14127