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Oestrogen‐related receptor alpha mediates chemotherapy resistance of osteosarcoma cells via regulation of ABCB1

Chemotherapy resistance is one of the major challenges for the treatment of osteosarcoma (OS). The potential roles of oestrogenic signals in the chemoresistance of OS cells were investigated. As compare to the parental cells, the doxorubicin and cisplatin (CDDP) resistant OS cells had greater levels...

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Detalles Bibliográficos
Autores principales: Chen, Yantao, Zhang, Kunshui, Li, Yang, Guo, Ruilian, Zhang, Kelin, Zhong, Guifang, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378180/
https://www.ncbi.nlm.nih.gov/pubmed/30609256
http://dx.doi.org/10.1111/jcmm.14123