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Impact of myo‐inositol trispyrophosphate (ITPP) on tumour oxygenation and response to irradiation in rodent tumour models

Tumour hypoxia is a well‐established factor of resistance in radiation therapy (RT). Myo‐inositol trispyrophosphate (ITPP) is an allosteric effector that reduces the oxygen‐binding affinity of haemoglobin and facilitates the release of oxygen by red blood cells. We investigated herein the oxygenatio...

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Detalles Bibliográficos
Autores principales: Tran, Ly‐Binh‐An, Cao‐Pham, Thanh‐Trang, Jordan, Bénédicte F., Deschoemaeker, Sofie, Heyerick, Arne, Gallez, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378184/
https://www.ncbi.nlm.nih.gov/pubmed/30575283
http://dx.doi.org/10.1111/jcmm.14092