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Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling

Recent emerging evidences revealed that epigenetic methylation of histone and DNA regulates the lineage commitment of mesenchymal progenitor cells. This study was undertaken to delineate the actions of histone lysine demethylase 7A (KDM7A) on osteogenic and adipogenic differentiation. Kdm7a expressi...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyue, Wang, Guannan, Wang, Yi, Zhou, Jie, Yuan, Hairui, Li, Xiaoxia, Liu, Ying, Wang, Baoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378189/
https://www.ncbi.nlm.nih.gov/pubmed/30614617
http://dx.doi.org/10.1111/jcmm.14126