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Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling
Recent emerging evidences revealed that epigenetic methylation of histone and DNA regulates the lineage commitment of mesenchymal progenitor cells. This study was undertaken to delineate the actions of histone lysine demethylase 7A (KDM7A) on osteogenic and adipogenic differentiation. Kdm7a expressi...
Autores principales: | Yang, Xiaoyue, Wang, Guannan, Wang, Yi, Zhou, Jie, Yuan, Hairui, Li, Xiaoxia, Liu, Ying, Wang, Baoli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378189/ https://www.ncbi.nlm.nih.gov/pubmed/30614617 http://dx.doi.org/10.1111/jcmm.14126 |
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