Alantolactone promotes ER stress‐mediated apoptosis by inhibition of TrxR1 in triple‐negative breast cancer cell lines and in a mouse model

Triple‐negative breast cancer (TNBC) is a subtype of breast cancer with poor clinical outcome and currently no effective targeted therapies are available. Alantolactone (ATL), a sesquiterpene lactone, has been shown to have potential anti‐tumour activity against various cancer cells. However, the un...

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Detalles Bibliográficos
Autores principales: Yin, Changtian, Dai, Xuanxuan, Huang, Xiangjie, Zhu, Wangyu, Chen, Xi, Zhou, Qiulin, Wang, Canwei, Zhao, Chengguang, Zou, Peng, Liang, Guang, Rajamanickam, Vinothkumar, Wang, Ouchen, Zhang, Xiaohua, Cui, Ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378194/
https://www.ncbi.nlm.nih.gov/pubmed/30609207
http://dx.doi.org/10.1111/jcmm.14139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378194/
https://www.ncbi.nlm.nih.gov/pubmed/30609207
http://dx.doi.org/10.1111/jcmm.14139

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