Effect of rapamycin on bone mass and strength in the α2(I)‐G610C mouse model of osteogenesis imperfecta

Osteogenesis imperfecta (OI) is commonly caused by heterozygous type I collagen structural mutations that disturb triple helix folding and integrity. This mutant‐containing misfolded collagen accumulates in the endoplasmic reticulum (ER) and induces a form of ER stress associated with negative effec...

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Detalles Bibliográficos
Autores principales: Bateman, John F., Sampurno, Lisa, Maurizi, Antonio, Lamandé, Shireen R., Sims, Natalie A., Cheng, Tegan L., Schindeler, Aaron, Little, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378195/
https://www.ncbi.nlm.nih.gov/pubmed/30597759
http://dx.doi.org/10.1111/jcmm.14072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378195/
https://www.ncbi.nlm.nih.gov/pubmed/30597759
http://dx.doi.org/10.1111/jcmm.14072

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