N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis

The abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase, plays a critical anti‐tumorigenic role...

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Detalles Bibliográficos
Autores principales: Zhuang, Changshui, Zhuang, Chengle, Luo, Xiaomin, Huang, Xinbo, Yao, Lv, Li, Jianfa, Li, Yawen, Xiong, Tiefu, Ye, Jing, Zhang, Fangting, Gui, Yaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://www.ncbi.nlm.nih.gov/pubmed/30648791
http://dx.doi.org/10.1111/jcmm.14128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://www.ncbi.nlm.nih.gov/pubmed/30648791
http://dx.doi.org/10.1111/jcmm.14128

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