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Pex11a deficiency causes dyslipidaemia and obesity in mice

Peroxisomes play a central role in lipid metabolism. We previously demonstrated that Pex11a deficiency impairs peroxisome abundance and fatty acid β‐oxidation and results in hepatic triglyceride accumulation. The role of Pex11a in dyslipidaemia and obesity is investigated here with Pex11a knockout m...

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Detalles Bibliográficos
Autores principales: Chen, Congcong, Wang, Hongwei, Chen, Bicheng, Chen, Deyuan, Lu, Chaosheng, Li, Haiyan, Qian, Yan, Tan, Yi, Weng, Huachun, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378206/
https://www.ncbi.nlm.nih.gov/pubmed/30585412
http://dx.doi.org/10.1111/jcmm.14108