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Genetic variant in miR‐21 binding sites is associated with colorectal cancer risk

Single nucleotide polymorphisms (SNPs) within binding sites of microRNAs (miRNAs) could modify cancer susceptibility by changing the binding affinity of miRNAs on their target mRNA 3ʹ‐untranslated regions (UTRs). MicroRNA‐21 (miR‐21) is involved in the development of colorectal cancer. However, the...

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Detalles Bibliográficos
Autores principales: Xie, Lisheng, Li, Shuwei, Jin, Jing, He, Lei, Xu, Kaili, Zhu, Lingjun, Du, Mulong, Liu, Yanqing, Chu, Haiyan, Zhang, Zhengdong, Wang, Meilin, Shi, Danni, Gu, Dongying, Ni, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378227/
https://www.ncbi.nlm.nih.gov/pubmed/30569605
http://dx.doi.org/10.1111/jcmm.14104