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Cell‐based high‐throughput screen for small molecule inhibitors of Bax translocation

Aberrant regulation of programmed cell death (PCD) has been tied to an array of human pathologies ranging from cancers to autoimmune disorders to diverse forms of neurodegeneration. Pharmacologic modulation of PCD signalling is therefore of central interest to a number of clinical and biomedical app...

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Detalles Bibliográficos
Autores principales: Hui, Kelvin Kai‐Wan, Dojo Soeandy, Chesarahmia, Chang, Stephano, Vizeacoumar, Frederick S., Sun, Thomas, Datti, Alessandro, Henderson, Jeffrey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378228/
https://www.ncbi.nlm.nih.gov/pubmed/30548903
http://dx.doi.org/10.1111/jcmm.14076