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Potential of Sodium MRI as a Biomarker for Neurodegeneration and Neuroinflammation in Multiple Sclerosis

In multiple sclerosis (MS), experimental and ex vivo studies indicate that pathologic intra- and extracellular sodium accumulation may play a pivotal role in inflammatory as well as neurodegenerative processes. Yet, in vivo assessment of sodium in the microenvironment is hard to achieve. Here, sodiu...

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Detalles Bibliográficos
Autores principales: Huhn, Konstantin, Engelhorn, Tobias, Linker, Ralf A., Nagel, Armin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378293/
https://www.ncbi.nlm.nih.gov/pubmed/30804885
http://dx.doi.org/10.3389/fneur.2019.00084