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Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion

Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with several potentially lethal complications. Higher levels of CD3+ T-cells in the graft have been associated with increased risk of graft-versus-host disease (GVHD), but also beneficial graft-versus-leukemia effect and reduced...

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Detalles Bibliográficos
Autores principales: Rådestad, Emelie, Sundin, Mikael, Törlén, Johan, Thunberg, Sarah, Önfelt, Björn, Ljungman, Per, Watz, Emma, Mattsson, Jonas, Uhlin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378311/
https://www.ncbi.nlm.nih.gov/pubmed/30804948
http://dx.doi.org/10.3389/fimmu.2019.00189