Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors

Ferroptotic death is a mechanism for tumor suppression by pharmacological inhibitors that target the X(c) (−) transporter (cystine/glutamate antiporter) in a host of non-CNS and CNS tumors. Inhibition of this transporter leads to reduction of cystine uptake, cyst(e)ine deprivation, subsequent deplet...

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Detalles Bibliográficos
Autores principales: Zille, Marietta, Kumar, Amit, Kundu, Nandini, Bourassa, Megan W., Wong, Victor S. C., Willis, Dianna, Karuppagounder, Saravanan S., Ratan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378329/
https://www.ncbi.nlm.nih.gov/pubmed/30783618
http://dx.doi.org/10.1523/ENEURO.0263-18.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378329/
https://www.ncbi.nlm.nih.gov/pubmed/30783618
http://dx.doi.org/10.1523/ENEURO.0263-18.2019

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