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Differential regulation of GSK-3β in spinal dorsal horn and in hippocampus mediated by interleukin-1beta contributes to pain hypersensitivity and memory deficits following peripheral nerve injury
Accumulating evidence shows that inhibition of glycogen synthase kinase-3beta (GSK-3β) ameliorates cognitive impairments caused by a diverse array of diseases. Our previous work showed that spared nerve injury (SNI) that induces neuropathic pain causes short-term memory deficits. Here, we reported t...
Autores principales: | Mai, Chun-Lin, Wei, Xiao, Gui, Wen-Shan, Xu, Ya-Nan, Zhang, Jun, Lin, Zhen-Jia, Tan, Zhi, Meng, Ying-Tong, Li, Yong-Yong, Zhou, Li-Jun, Liu, Xian-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378430/ https://www.ncbi.nlm.nih.gov/pubmed/30632435 http://dx.doi.org/10.1177/1744806919826789 |
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