TLR4 mediates upregulation and sensitization of TRPV1 in primary afferent neurons in 2,4,6-trinitrobenzene sulfate-induced colitis

Elevated excitability of primary afferent neurons underlies chronic pain in patients with functional or inflammatory bowel diseases. Recent studies have established an essential role for an enhanced transient receptor potential vanilloid subtype 1 (TRPV1) signaling in mediating peripheral hyperalges...

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Detalles Bibliográficos
Autores principales: Wu, Yingwei, Wang, Yingping, Wang, Juan, Fan, Qi, Zhu, Jinyu, Yang, Liu, Rong, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378437/
https://www.ncbi.nlm.nih.gov/pubmed/30672380
http://dx.doi.org/10.1177/1744806919830018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378437/
https://www.ncbi.nlm.nih.gov/pubmed/30672380
http://dx.doi.org/10.1177/1744806919830018

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