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TLR4 mediates upregulation and sensitization of TRPV1 in primary afferent neurons in 2,4,6-trinitrobenzene sulfate-induced colitis
Elevated excitability of primary afferent neurons underlies chronic pain in patients with functional or inflammatory bowel diseases. Recent studies have established an essential role for an enhanced transient receptor potential vanilloid subtype 1 (TRPV1) signaling in mediating peripheral hyperalges...
Autores principales: | Wu, Yingwei, Wang, Yingping, Wang, Juan, Fan, Qi, Zhu, Jinyu, Yang, Liu, Rong, Weifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378437/ https://www.ncbi.nlm.nih.gov/pubmed/30672380 http://dx.doi.org/10.1177/1744806919830018 |
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