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Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists
Human and animal studies suggest an intriguing relationship between the immune system and the development of depression. Some peripherally produced cytokines, such as TNF-α, can cross the blood brain barrier and result in activation of brain microglia which produces additional TNF-α and fosters a ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378555/ https://www.ncbi.nlm.nih.gov/pubmed/30804748 http://dx.doi.org/10.3389/fnins.2019.00098 |