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Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists

Human and animal studies suggest an intriguing relationship between the immune system and the development of depression. Some peripherally produced cytokines, such as TNF-α, can cross the blood brain barrier and result in activation of brain microglia which produces additional TNF-α and fosters a ca...

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Detalles Bibliográficos
Autores principales:	Brymer, Kyle J., Romay-Tallon, Raquel, Allen, Josh, Caruncho, Hector J., Kalynchuk, Lisa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378555/ https://www.ncbi.nlm.nih.gov/pubmed/30804748 http://dx.doi.org/10.3389/fnins.2019.00098

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