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Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice

Antibody‐mediated immunity is highly protective against disease. The majority of current vaccines confer protection through humoral immunity, but there is high variability in responsiveness across populations. Identifying immune mechanisms that mediate low antibody responsiveness may provide potenti...

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Detalles Bibliográficos
Autores principales: Poyntz, Hazel C, Jones, Angela, Jauregui, Ruy, Young, Wayne, Gestin, Aurélie, Mooney, Anna, Lamiable, Olivier, Altermann, Eric, Schmidt, Alfonso, Gasser, Olivier, Weyrich, Laura, Jolly, Christopher J, Linterman, Michelle A, Gros, Graham Le, Hawkins, Edwin D, Forbes‐Blom, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378622/
https://www.ncbi.nlm.nih.gov/pubmed/30152893
http://dx.doi.org/10.1111/imcb.12199